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Year : 2013  |  Volume : 4  |  Issue : 2  |  Page : 167  

First-born may be at greater risk for diabetes and hypertension


Department of Pharmacology, Indira Gandhi Medical College and Research Institute, Kadhirkamam, Puducherry, India

Date of Web Publication20-Apr-2013

Correspondence Address:
G Sivagnanam
Department of Pharmacology, Indira Gandhi Medical College and Research Institute, Kadhirkamam, Puducherry
India
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Source of Support: None, Conflict of Interest: None


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How to cite this article:
Sivagnanam G. First-born may be at greater risk for diabetes and hypertension. J Pharmacol Pharmacother 2013;4:167

How to cite this URL:
Sivagnanam G. First-born may be at greater risk for diabetes and hypertension. J Pharmacol Pharmacother [serial online] 2013 [cited 2019 Jul 23];4:167. Available from: http://www.jpharmacol.com/text.asp?2013/4/2/167/110925


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Researchers think better flow of nutrients to the womb in subsequent pregnancies might explain why. [1]


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In a study that aimed to assess the association of birth order with changes in metabolism in childhood, it has been found that the first-borns were taller and slimmer, with reduced insulin sensitivity (by 21%) and increased day-time blood pressure (+5 mm Hg) compared to later-borns. [2]

First-born children having such risk factors may have to be screened with or followed for later development of diabetes and hypertension. However, the authors point that their finding may have serious public health implications for countries like China with a one child policy (and nearly half the population of India wherein two child norm is almost the order of the day).
"Is it a curse to be born first?" is the question posed by those who surfaced first.

 
   References Top

1.Available from: http://www.nlm.nih.gov/medlineplus/news/fullstory_133941.html. [Last accessed 2013 Feb 18].  Back to cited text no. 1
    
2.Ayyavoo A, Savage T, Derraik JG, Hofman PL, Cutfield WS. First-born children have reduced insulin sensitivity and higher daytime blood pressure compared to later-born children. J Clin Endocrinol Metab 2013 [Epub ahead of print].  Back to cited text no. 2
    




 

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