Journal of Pharmacology and Pharmacotherapeutics

CASE REPORT
Year
: 2017  |  Volume : 8  |  Issue : 1  |  Page : 41--43

Pleural tuberculosis following infliximab therapy for ankylosing spondylitis


Vs Gokul Krishnan, Sharath Madhyastha, Kusugodlu Ramamoorthi, Raviraj V Acharya, Vinaya Gopalaswamy 
 Department of Medicine, Kasturba Medical College, Manipal, Karnataka, India

Correspondence Address:
Sharath Madhyastha
Department of Medicine, Kasturba Medical College, Manipal - 576 104, Karnataka
India

We present a case of pleural tuberculosis (TB) in a patient on infliximab for ankylosing spondylitis. A 36-year-old male presented to our hospital with low back ache of inflammatory type along with multiple symmetric inflammatory type of joint pain. Further clinical examination, laboratory and radiological investigations were suggestive of ankylosing spondylitis. He was initially treated with nonsteroidal anti-inflammatory drugs but citing poor response it was decided to initiate biologic therapy using infliximab (antitumor necrosis factor-alpha). Mantoux test and chest radiograph were done before the therapy to rule out TB. Following three doses of infliximab, patient came with complaints of fever and cough for 1 week. On investigation, it was found to be a case of pulmonary TB. This shows the importance of close monitoring of patient for TB among patients on infliximab even though the screening test has come out to be negative.


How to cite this article:
Gokul Krishnan V s, Madhyastha S, Ramamoorthi K, Acharya RV, Gopalaswamy V. Pleural tuberculosis following infliximab therapy for ankylosing spondylitis.J Pharmacol Pharmacother 2017;8:41-43


How to cite this URL:
Gokul Krishnan V s, Madhyastha S, Ramamoorthi K, Acharya RV, Gopalaswamy V. Pleural tuberculosis following infliximab therapy for ankylosing spondylitis. J Pharmacol Pharmacother [serial online] 2017 [cited 2019 Aug 21 ];8:41-43
Available from: http://www.jpharmacol.com/article.asp?issn=0976-500X;year=2017;volume=8;issue=1;spage=41;epage=43;aulast=Gokul;type=0