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  Indian J Med Microbiol
 

Figure 3: Effects of U73122, xestospongin C, and SKF-96365 on the gentamicin-induced [Ca2+]i elevation. Gentamicin (500 μM) was antagonized by U73122 (10 μM), xestospongin C (2 μM), and SKF-96365 (10 μM). The upper trace shows the effect of U73122 on the gentamicin-induced [Ca2+]i elevation. In the lower graph, white columns represent the [Ca2+]i elevated by gentamicin alone. Data are mean ± SEM, N = 8 (U73122), 14 (xestospongin C), or 32 (SKF-96365). ****P < 0.001 compare to corresponding pretreated values

Figure 3: Effects of U73122, xestospongin C, and SKF-96365 on the gentamicin-induced [Ca<sup>2+</sup>]i elevation. Gentamicin (500 μM) was antagonized by U73122 (10 μM), xestospongin C (2 μM), and SKF-96365 (10 μM). The upper trace shows the effect of U73122 on the gentamicin-induced [Ca<sup>2+</sup>]i elevation. In the lower graph, white columns represent the [Ca<sup>2+</sup>]i elevated by gentamicin alone. Data are mean ± SEM, N = 8 (U73122), 14 (xestospongin C), or 32 (SKF-96365). ****<i>P</i> < 0.001 compare to corresponding pretreated values