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  Indian J Med Microbiol
 

Figure 8: Antagonism of nifedipine responses by NPS2390. Cells were inhibited with various concentrations of NPS2390 (1-10 μM) prior to the addition of nifedipine. Upper panel: representative trace showing the inhibition of the nifedipine-induced [Ca2+]i elevation by NPS2390 (5 μM). Lower panel: [Ca2+]i elevation by NPS2390 (5 μM). Lower panel: Ca2+ responses to nifedipine in the absence (º) and presence () of NPS2390. Data are mean ± SEM, N = 29 (1 μM), 42 (2 26 (5 or 30 (10 ****P < 0.001 compare to corresponding pretreated values

Figure 8: Antagonism of nifedipine responses by NPS2390. Cells were inhibited with various concentrations of NPS2390 (1-10 μM) prior to the addition of nifedipine. Upper panel: representative trace showing the inhibition of the nifedipine-induced [Ca<sup>2+</sup>]i elevation by NPS2390 (5 μM). Lower panel: [Ca<sup>2+</sup>]i elevation by NPS2390 (5 μM). Lower panel: Ca<sup>2+</sup> responses to nifedipine in the absence (º) and presence () of NPS2390. Data are mean ± SEM, N = 29 (1 μM), 42 (2 26 (5 or 30 (10 ****<i>P</i> < 0.001 compare to corresponding pretreated values