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  Indian J Med Microbiol
 

Figure 1: Effect of TLK48462 on nociceptive response to formalin injection. (a) Reduction in the duration of paw licking and lifting in response to an intraplantar injection of formalin in TLK48462-treated-mice and indomethacin (IDM)-treated mice, compared with control. (b) Area under the curve show significant decreases during phase 1 (0-10 min) and during phase 2 (15-45 min) in TKL48462-treated-mice and IDM-treated-mice, compared with control (cont). Statistical analysis was performed by Student's t-test. A P value less than 0.05 was considered as significant

Figure 1: Effect of TLK48462 on nociceptive response to formalin injection. (a) Reduction in the duration of paw licking and lifting in response to an intraplantar injection of formalin in TLK48462-treated-mice and indomethacin (IDM)-treated mice, compared with control. (b) Area under the curve show significant decreases during phase 1 (0-10 min) and during phase 2 (15-45 min) in TKL48462-treated-mice and IDM-treated-mice, compared with control (cont). Statistical analysis was performed by Student's t-test. A P value less than 0.05 was considered as significant