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  Indian J Med Microbiol
 

Figure 5: Effects of asenapine on cytosolic Ca2+ in H9C2 in the presence or absence of serotoninergic and dopaminergic receptor blockers and L- and T-type Ca2+ channels inhibitors. An example of each experimental protocol is shown. (a) 2 min asenapine (A) with 5-HT1Ainhibitor, NAD-299 (NAD); (b) with L type Ca2+ channel blocker, amlodipine (Amlod); (c) with T type Ca2+ channel blocker, ML218; (d) with D2 receptor inhibitor, propionyl promazine (Propionyl); (e) with 5-HT2Ainhibitor, nefazodone (Nefaz). The layout is the same as in Figure 3

Figure 5: Effects of asenapine on cytosolic Ca<sup>2+</sup> in H9C2 in the presence or absence of serotoninergic and dopaminergic receptor blockers and L- and T-type Ca<sup>2+</sup> channels inhibitors. An example of each experimental protocol is shown. (a) 2 min asenapine (A) with 5-HT<sub>1A</sub>inhibitor, NAD-299 (NAD); (b) with L type Ca<sup>2+</sup> channel blocker, amlodipine (Amlod); (c) with T type Ca<sup>2+</sup> channel blocker, ML218; (d) with D2 receptor inhibitor, propionyl promazine (Propionyl); (e) with 5-HT<sub>2A</sub>inhibitor, nefazodone (Nefaz). The layout is the same as in Figure 3