Year : 2013  |  Volume : 4  |  Issue : 4  |  Page : 300-302

A rare case of ethambutol induced pulmonary eosinophilia

1 Department of Pulmonary Medicine, Burdwan Medical College and Hospital, Burdwan, India
2 Department of Pulmonary Medicine, R G Kar Medical College, Kolkata, India
3 Department of Pulmonary Medicine, NRS Medical College and Hospital, Shealdah, Kolkata, West Bengal, India

Correspondence Address:
Kaushik Saha
Rabindra Pally, 1st Lane, P.O. - Nimta, Kolkata - 700 049, West Bengal
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0976-500X.119724

Rights and Permissions

Antitubercular drug (ATD) induced eosinophilic lung disease is a rare phenomenon. It usually occurs due to isoniazid and para amino salicylic acid. A 34-year-male of sputum positive pulmonary tuberculosis, on antitubercular drugs (rifampicin, isoniazid, ethambutol, and pyrazinamide) for last 3 weeks, presented with generalized arthralgia and maculopapular rash for last 2 weeks and shortness of breath for last 1 week. Chest X-ray and High resolution computerized tomographic scan thorax showed bilateral peripheral airspace opacification. Bronchoalveolar lavage revealed 51% eosinophils of total cellularity (1200/cmm) confirming the diagnosis of pulmonary eosinophilia. ATD was stopped for 2 weeks and then reintroduced one by one. Patient again developed similar kind of symptoms with reintroduction of ethambutol. According to criteria for drug induced pulmonary eosinophilia, he was diagnosed as a case of ethambutol induced pulmonary eosinophilia.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded336    
    Comments [Add]    
    Cited by others 2    

Recommend this journal