Phosphodiesterase-4 inhibition with rolipram attenuates hepatocellular injury in hyperinflammation in vivo and in vitro without influencing inflammation and HO-1 expression
Jakob Wollborn1, Christian Wunder1, Jana Stix2, Winfried Neuhaus3, Rapahel R Bruno1, Wolfgang Baar4, Sven Flemming5, Norbert Roewer1, Nicolas Schlegel5, Martin A Schick1
1 Department of Anaesthesia and Critical Care, University Hospital Würzburg, Germany 2 Department of Pathology, Klinikum Nürnberg, Nürnberg, Germany 3 Department of Anaesthesia and Critical Care, University Hospital Würzburg, Germany; Department of Medicinal Chemistry, University of Vienna, Vienna, Austria 4 Department of Anaesthesia and Critical Care, University Hospital Würzburg; Department of Anesthesiology and Critical Care Medicine, University Medical Center, Freiburg, Germany 5 Department of General, Visceral, Vascular, and Paediatric Surgery (Department of Surgery I), University of Würzburg, Würzburg, Germany
Correspondence Address:
Martin A Schick Department of Anaesthesia and Critical Care, University Hospital Würzburg Germany
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0976-500X.149138
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