| CASE REPORT |
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| Year : 2015 | Volume
: 6
| Issue : 2 | Page : 105-106 |
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Hypersensitivity reaction with deferasirox
Atul Sharma1, Ekta Arora2, Harmanjit Singh2
1 Department of Medicine, Smt. Sucheta Kriplani Hospital and Lady Hardinge Medical College (LHMC), New Delhi, India
2 Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India
Correspondence Address:
Atul Sharma
Department of Medicine, Smt. Sucheta Kriplani Hospital and Lady Hardinge Medical College, New Delhi
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0976-500X.155491
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Thalassemias comprise a group of hereditary blood disorders. Thalassemia major presents with anemia within the first 2 years of life requiring frequent blood transfusions for sustaining life. Regular blood transfusions lead to iron overload-related complications. Prognosis of thalassemia has improved because of the availability of iron-chelating agents. Oral iron chelators are the mainstay of chelation therapy. Deferasirox is a new-generation oral iron chelator for once daily usage. We herein describe a patient of beta thalassemia major who developed an allergic manifestation in the form of erythematous pruritic skin rashes to the oral iron chelator deferasirox. This is a rare adverse reaction reported with deferasirox that led to a therapeutic dilemma in this particular case. |
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