Journal of Pharmacology and Pharmacotherapeutics

CASE REPORT
Year
: 2013  |  Volume : 4  |  Issue : 2  |  Page : 155--157

Diclofenac induced acute renal failure in a decompensated elderly patient


Pallavi Dhanvijay, Arup K Misra, Sushil K Varma 
 Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra, India

Correspondence Address:
Pallavi Dhanvijay
Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra
India

Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly prescribed drugs in post-operative period worldwide. Their nephrotoxic effects are documented and accounts for around 15.5% of all cases of drug induced renal failure. Acute renal failure following NSAIDs usage are reported in volume depleted patients which is further precipitated by co-morbid conditions like hypertension and various drug interactions that increase plasma level of NSAIDs and worsens the condition. This highlights the importance of hydration in post-operative period as well as assessment of co-morbid conditions before administration of NSAIDs to prevent acute renal failure.


How to cite this article:
Dhanvijay P, Misra AK, Varma SK. Diclofenac induced acute renal failure in a decompensated elderly patient.J Pharmacol Pharmacother 2013;4:155-157


How to cite this URL:
Dhanvijay P, Misra AK, Varma SK. Diclofenac induced acute renal failure in a decompensated elderly patient. J Pharmacol Pharmacother [serial online] 2013 [cited 2021 Oct 15 ];4:155-157
Available from: http://www.jpharmacol.com/article.asp?issn=0976-500X;year=2013;volume=4;issue=2;spage=155;epage=157;aulast=Dhanvijay;type=0