Journal of Pharmacology and Pharmacotherapeutics

CASE REPORT
Year
: 2015  |  Volume : 6  |  Issue : 3  |  Page : 169--171

Intestinal pseudo-obstruction following oral baclofen: An unusual complication


Vilvapathy Senguttuvan Karthikeyan1, Kuppusamy Senthilkumaran1, Bettaiyagowder Easwaran1, Rajamariappan Rajbhaskar2 
1 Department of General Surgery, Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry, India
2 Department of Neurosurgery, Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry, India

Correspondence Address:
Vilvapathy Senguttuvan Karthikeyan
Department of General Surgery, Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry - 605 102
India

Baclofen is a gamma- aminobutyric acid B (GABA B) agonist used for the management of spasticity associated with spinal cord injury. Oral baclofen might cause constipation, but intestinal pseudo-obstruction is very rare. We report a 50-year-old male with spasticity following cervical discectomy (C3-4) on oral baclofen for 6 months with intestinal pseudo-obstruction. He had undergone open suprapubic cystostomy for traumatic urethral injury, 45 days prior to the presentation and adhesive intestinal obstruction was also considered a possibility. However, there were no air fluid levels on abdominal radiographs and ultrasound abdomen was non-contributory. Withdrawal of baclofen was therapeutic in this patient. This case is being reported to highlight the rare possibility of oral baclofen induced intestinal pseudo-obstruction.


How to cite this article:
Karthikeyan VS, Senthilkumaran K, Easwaran B, Rajbhaskar R. Intestinal pseudo-obstruction following oral baclofen: An unusual complication.J Pharmacol Pharmacother 2015;6:169-171


How to cite this URL:
Karthikeyan VS, Senthilkumaran K, Easwaran B, Rajbhaskar R. Intestinal pseudo-obstruction following oral baclofen: An unusual complication. J Pharmacol Pharmacother [serial online] 2015 [cited 2021 Oct 24 ];6:169-171
Available from: http://www.jpharmacol.com/article.asp?issn=0976-500X;year=2015;volume=6;issue=3;spage=169;epage=171;aulast=Karthikeyan;type=0