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  Indian J Med Microbiol
 

Figure 3: Histopathology of spleen (H and E stain, ×40). (a) Normal control group— normal morphology; (b) disease control group— severe (score 6) epithelioid cells (E), lymphocyte (L) infi ltrate with caseation necrosis (CN), and giant cells (G); (c– e) isoniazid, rifampicin, and CSHMC (20 mg/kg) treated group— minimal to mild (score 1– 1.5) epithelioid cells infi ltration with no caseation necrosis and giant cell; (f) CSHMC (5 mg/kg) treated group— mild to moderate (score 2.5) epithelioid cells infi ltration with no caseation necrosis and giant cell

Figure 3: Histopathology of spleen (H and E stain, ×40). (a) Normal control group— normal morphology; (b) disease control group— severe (score 6) epithelioid cells (E), lymphocyte (L) infi ltrate with caseation necrosis (CN), and giant cells (G); (c– e) isoniazid, rifampicin, and CSHMC (20 mg/kg) treated group— minimal to mild (score 1– 1.5) epithelioid cells infi ltration with no caseation necrosis and giant cell; (f) CSHMC (5 mg/kg) treated group— mild to moderate (score 2.5) epithelioid cells infi ltration with no caseation necrosis and giant cell