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  Indian J Med Microbiol
 

Figure 2: Structural requirement of disaccharides for hepatocyte growth factor (HGF)-inducing activity. Active and inactive disaccharides are summarized. The N-sulfation and/or 6-O-sulfation of the glucosamine residue provides the disaccharide with HGF-inducing activity. The 2-O-sulfated group in the residue of hexuronic acid canceled the effect of N-sulfated and/or 6-O-sulfated disaccharides

Figure 2: Structural requirement of disaccharides for hepatocyte growth factor (HGF)-inducing activity. Active and inactive disaccharides are summarized. The <i>N</i>-sulfation and/or 6-<i>O</i>-sulfation of the glucosamine residue provides the disaccharide with HGF-inducing activity. The 2-<i>O</i>-sulfated group in the residue of hexuronic acid canceled the effect of <i>N</i>-sulfated and/or 6-<i>O</i>-sulfated disaccharides