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  Indian J Med Microbiol
 

Figure 5: Immunohistochemical staining of a-smooth muscle actin (×200) in the skin tissues of (a) The control group showing minimal positive staining for a smooth muscle actin; (b) Bleomycin group showing diffuse positive staining for a smooth muscle actin which is marked in the hypdermal layer; (c) Bleomycin + valproic acid group showing mild positive staining for a smooth muscle actin; (d) Valproic acid group revealing minimal positive staining for a smooth muscle actin; (e) Percentage of a-smooth muscle actin positive immunostaining. Data are expressed as mean ± standard error of the mean. ***Means P < 0.001 compared to control group, ###means P < 0. 001 compared to bleomycin group

Figure 5: Immunohistochemical staining of a-smooth muscle actin (×200) in the skin tissues of (a) The control group showing minimal positive staining for a smooth muscle actin; (b) Bleomycin group showing diffuse positive staining for a smooth muscle actin which is marked in the hypdermal layer; (c) Bleomycin + valproic acid group showing mild positive staining for a smooth muscle actin; (d) Valproic acid group revealing minimal positive staining for a smooth muscle actin; (e) Percentage of a-smooth muscle actin positive immunostaining. Data are expressed as mean ± standard error of the mean. ***Means <i>P</i> < 0.001 compared to control group, <sup>###</sup>means <i>P</i> < 0. 001 compared to bleomycin group