Ethionamide-induced gynecomastia

• Ramakant Dixit^1*,
• Jacob George¹,
• Arun K. Sharma²,
• Naveen chhabra²,
• Suresh K. Jangir¹,
• Vikas Mishra¹

1. ¹Departments of Respiratory Medicine, College, Ajmer, India ABSTRACT Gynecomastia is very rare during antituberculosis chemotherapy. We describe a 38-year-old male patient who developed a painful gynecomastia following second-line drug therapy for multidrug-resistant pulmonary tuberculosis. Gynecomastia disappeared after stopping the ethionamide. A published literature on antituberculosis-induced gynecomastia is also briefly discussed. Key words: Antituberculosis therapy, drug-induced gynecomastia, ethionamide.
2. ²Pharmacology and Experimental Therapeutics, J. L. N. Medical College, Ajmer, India ABSTRACT Gynecomastia is very rare during antituberculosis chemotherapy. We describe a 38-year-old male patient who developed a painful gynecomastia following second-line drug therapy for multidrug-resistant pulmonary tuberculosis. Gynecomastia disappeared after stopping the ethionamide. A published literature on antituberculosis-induced gynecomastia is also briefly discussed. Key words: Antituberculosis therapy, drug-induced gynecomastia, ethionamide.

Published in Journal of Pharmacology and Pharmacotherapeutics