How to calculate sample size in animal studies?

Charan, Jaykaran; Kantharia, N. D.

doi:10.4103/0976-500X.119726

Educational ForumArchivesVol. 4 | Issue 4 | 2013 | pp. 303–304Open Access

How to calculate sample size in animal studies?

¹^*,
¹

¹Department of Pharmacology, GMERS Medical College, Patan, Government Medical College, Surat, Gujarat, India.

Correspondence: Jaykaran Charan
Department of Pharmacology, GMERS Medical College, Patan, Government Medical College, Surat, Gujarat, India.
Email: drjaykaran@yahoo.co.in

Published: Jan 1, 2013

DOI: https://doi.org/10.4103/0976-500X.119726
Article URL: https://www.jpharmacol.com/article/j-pharmacol-pharmacother-4-4-303
PDF URL: https://www.jpharmacol.com/article/j-pharmacol-pharmacother-4-4-303.pdf

Abstract

Calculation of sample size is one of the important component of design of any research including animal studies. If a researcher select less number of animals it may lead to missing of any significant difference even if it exist in population and if more number of animals selected then it may lead to unnecessary wastage of resources and may lead to ethical issues. In this article, on the basis of review of literature done by us we suggested few methods of sample size calculations for animal studies.

Keywords

Subject

Readers Also Viewed

Original Research Article

Pharmacogenomics Meets Generative AI: Transforming Clinical Trial Design with Large Language Models

Annisa Fatharani, Ali Alsayegh

Jan 1, 2026

Review Article

Clinical Outcomes and Management of Post-varicocelectomy on Male Fertility: A Comprehensive Review

Mohammad Akbar Hossain

Jan 1, 2026

Original Research Article

Knowledge, Attitude, and Practice on Digital Eye Strain Among Healthcare Students at a Private University in Northern Peninsular Malaysia

Lim Chin Hung, Subramani Parasuraman, Sam Aaseer Thamby

Jan 1, 2026