Ganciclovir–tenofovir interaction leading to tenofovir‑induced nephrotoxicity
- 1*,
- 1,
- 2,
- 2
- 1Departments of Clinical Pharmacology and Therapeutics, Institute of Medical Sciences, Hyderabad, Telangana, India.
- 2General Medicine, Nizam’s Institute of Medical Sciences, Hyderabad, Telangana, India.
Published in Journal of Pharmacology and Pharmacotherapeutics
Correspondence: Radhika Soanker
Departments of Clinical Pharmacology and Therapeutics, Institute of Medical Sciences, Hyderabad, Telangana, India.
Copyright: © 2014 The Author(s). This is an open access article.
Published: Jan 1, 2014, Received: Dec 30, 2013, Accepted: Apr 25, 2014
Abstract
Viral enteritis is an important gastrointestinal disorder in human immunodeficiency virus (HIV)‑infected patients. Cytomegalovirus (CMV) is the most common opportunistic agent in these patients. As ganciclovir and tenofovir are the most commonly used drugs for the treatment of CMV and HIV infection, respectively, this case report showcases the potentiality of drug interaction as well as the safety measures to be taken when using these two drugs together in unavoidable situations.
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